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We demonstrated that ligands with distinct chemical structures uniquely bind to the receptor, resulting in diverse conformations and biasing signal transduction

We then discuss in detail the metal nanomedicines that have been extensively applied in synergistic cancer therapy, including chemotherapy, photodynamic therapy (PDT), sonodynamic therapy (SDT), chemodynamic therapy (CDT), ferroptotic therapy, and radiotherapy

The trade-off is that lower concentrations deplete the vial faster across multiple doses

Furthermore, epithelial cells are held together by tight junctions (TJs) and adherens junctions (AJs), both essential for maintaining epithelial barrier integrity