glp 1 aafp Determining When to Recommend Glucose-Lowering Drugs That Reduce Cardiovascular Risk Free CME Available: Prescribing GLP-1

When estrogen levels drop, skin becomes drier with more wrinkles, and taurine was shown to upregulate zonulin, claudin-11, and other tight junction proteins along with type III collagen in a way that mimics the effect of estradiol.[ref] Possibly helps with skin aging effects: A Mendelian randomization study found that genetic variants that are associated with increased taurine levels are also associated with decreased skin aging effects.[ref] In animal studies, higher taurine levels (added to their water) helped to prevent UV-induced wrinkles

J Chromatogr 1994

Freitag, T.L

But its likely due to compounds in coffee called polyphenols, not the caffeine specifically