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Moreover, endothelial cell inflammation results in the proliferation, migration, and apoptosis of vascular smooth muscle cells (VSMCs), thereby fostering intimal thickening and vascular remodeling and accelerating the deposition of atherosclerotic plaques [6]

The investigators used telomerase-negative human fetal fibroblast lines, treating with Epithalon at multiple concentrations and measuring telomerase activity by TRAP assay and telomere length by Southern blot

Pearson, S

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