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Importantly, these effects occur without changes in food intake, indicating metabolic rather than anorectic mechanisms

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Similarly, authors [3] of the first double-blind, randomized, placebo-controlled clinical trial of oral glutathione supplementation performed in healthy adult humans concluded that despite the biochemical plausibility, optimal dose, recommended timing of administration and appropriate choice of outcome measures, no significant changes were observed in oxidative stress biomarkers or erythrocyte glutathione concentrations following 4 weeks of oral (2 x 500mg daily) glutathione supplementation

Preliminary studies suggest that liposomes optimize absorption by protecting the GSH from oxidation