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Available from: Hendrick V, et al

Beyond cholesterol alone, semaglutide lowered blood pressure, reduced inflammation markers, and improved overall cardiovascular outcomessuggesting benefits that extend beyond lipid changes

Working-age populations favor once-weekly injections over daily pills, reinforcing uptake

Considering that LCN-2 could function as a biomechanical and inflammatory sensor in bonecartilage crosstalk, its specific role in IVDD needs to be elucidated ( Fibroblast growth factor-23 (FGF-23) is the first identified osteokine that can bind to the tyrosine kinase FGF receptors (FGFRs) to regulate phosphate and vitamin D metabolism (116)