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Resuspended resin just means that you want to invert the bottle of agarose resin a few times to make sure that all the beads are off the bottom of the bottle and in solution before you pipet some out of there

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This clinical observation is possibly because the methylcobalamin delivered by this method is better absorbed into the bloodstream, or it is more bio-available, or the effect is more noticeable because of the constantly higher blood level