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SGLT2i have shown robust effects in reducing heart failure hospitalization and slowing the progression of chronic kidney disease, while GLP-1 RAs have demonstrated superior efficacy in reducing atherothrombotic events, particularly non-fatal stroke

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So, having humility around what you think you know and dont know is very helpful

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Mller et al., 2019)

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For constipation management, increasing dietary fiber gradually (not suddenly, which can worsen symptoms), drinking at least 60 to 80 ounces of water daily, and incorporating light movement like walking can provide relief without medication

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