Furthermore, their capacity to accumulate carotenoids and betalains positions them as a relevant functional vegetable for the development of foods with antioxidant and nutraceutical properties (Matas et al., 2024
For example, we observed multiple changes in mitochondrial activity levels, particularly for the GLP1R/GIPR/GCGR extended interaction network associated with HF, mitochondrial diseases, and the combined list of all known mitochondrial genes
F2-IsoPs are effective vasoconstrictors that induce mitogenesis in vascular smooth muscle cells
Specifically, gut microbiota dysbiosis, such as increased abundance of Proteobacteria and Actinobacteria and decreased numbers of Bacteroidetes , Prevotella and Firmicutes phyla , reduces the expression of tight junction protein genes, directly leading to the impairment of intestinal barrier function, making harmful microbiota and microorganisms pass through the intestinal barrier, stimulating the immune system and inducing immune cell inflammation, and ultimately accelerating NAFLD and liver fibrosis (58, 59)
