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Potential risks around fertility, pregnancy, or breastfeeding remain completely unstudied

Therefore, recognition of serine deficiency in LC is highly important because serine therapy has shown promising outcomes in neurological conditions (49) and in reducing depression and cognitive impairment (50)

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Although these analyses are not specific to the central nervous system (CNS), they do offer clues to ongoing brain injury pathogenesis, as the increased permeability of the bloodbrain barrier (BBB) after TBI allows for greater exchange of CNS/peripheral solutes, and many of these metabolites are also detected in the brain parenchyma [34]