It was first created to treat type 2 diabetes and has been shown to reduce blood sugar levels, reduce the risk of heart disease, and improve metabolic parameters
Curr Gastroenterol Rep 12:319330
219 The antiarthritic potential of this formulation has been evidenced by its capacity in suppressing CRP, CD4 + and CD8 T + cells, Th 17 cells, B cells, miRNA-155, miRNA-138, miRNA-16 and VAS score, and augmenting Treg cells without any adverse events in the clinical trials involving osteoarthritis and RA patients
In a Dextran Sulfate Sodium-induced colitis model, oral administration of ganoderic acid enriched beneficial microbial taxa, including Lactobacillus and Oscillospira , while reducing the abundance of pathogenic bacteria