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Treatment requires specialist prescribing, regular monitoring for adverse effects including pancreatitis, and integration with lifestyle modifications

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Therefore, inhibiting the release of glucagon is crucial when blood glucose levels need to be lowered

It is worth mentioning that we also used univariable MR (UVMR) and multivariable MR (MVMR) analyses to identify the risk factors whose effects on MASLD were independent of BMI to figure out whether the causal effect of GLP-1R-based agonists on MASLD was fully dependent on their weight-loss effect