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Although coffee and caffeine can increase the risk of cardiovascular disease, numerous studies have demonstrated that coffee and caffeine have hepatoprotective effects against chronic liver diseases ( Camellia sinensis (in the Theaceae family) and includes several varieties, such as green and black tea ( in vitro and in vivo studies on caffeine and EGCG, which provide biological plausibility for their effects ( In the present study, we used a high trans fatty acid/high-carbohydrate (HFHC) diet-induced NASH mouse model to compare the effects of caffeine and EGCG on liver fat metabolism, glucose metabolism, inflammation, and liver fibrosis

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