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3 To prevent excessive oxidative stress and maintain favorable redox homeostasis, tumor cells have evolved a complex antioxidant defense system that strategically adjusts multiple antioxidant enzymes such as catalase, glutathione reductase, and antioxidant molecules

Similarly, high levels of membrane-spanning protein CD133 is associated with HNSCC invasiveness and metastasis [58]

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However, if you have a condition that puts you at risk for deficiency, supplementing with at least 2.5 micrograms daily is recommended