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Across Cam3.II R539T and Cam3.II C580Y , compared to their isogenic sensitive isolate Cam3.II REV (isolates from Pursat Province, Cambodia) in both 3-6 hpi ring-(Fig 1) and in 24 hpi trophozoite-stage parasites (previously published) 9 , we found three proteins to be consistently dysregulated in abundance

This is a significant (p 100-fold decrease compared to the untreated control, where Fe and Zn were found at concentrations of 0.007 and 0.001 g/mL, respectively

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