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The microbial tryptophan metabolite indole acts on the gastrointestinal tract to improve glucose homeostasis in a mouse model of diabetes by enhancing GLP-1 secretion and L cell differentiation

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Visual indicators Cloudiness: The solution should be clear and colorless

Tirzepatide represents a dual agonist, targeting both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors, which may explain its enhanced efficacy in clinical trials