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Summary: Mounjaro (tirzepatide) can be used after gastric sleeve surgery under specialist supervision, though clinical experience is limited and the decision must be individualised based on weight trajectory, metabolic control, and tolerability
Thanks to its structural modifications, Semaglutide offers extended activity compared to natural GLP-1, enabling the investigation of prolonged receptor interactions and regulatory feedback mechanisms
Asymptomatic diabetic cardiomyopathy: an underrecognized entity in type 2 diabetes
Neural mechanism underlying leptin function In the brain, leptin transmits the peripheral lipid and glucose metabolic information, activates leptin signaling pathways and elicits a cascade of reactions, leading to reduced feeding, decreased appetite, enhanced mitochondrial oxidation and elevated thermogenesis [12]
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