I'm in the US and seems the loading dose protocol here is unfortunately less aggressive
It helps increase neural communication which takes energy, and the body will naturally grab that energy from stored fat or dietary nutrients
9 The GLP-1RA (glucagon-like peptide-1 receptor agonist), semaglutide, is approved at a dose of 2.4 mg once weekly, administered subcutaneously, for long-term weight management and cardiovascular risk reduction
Preclinical models demonstrate that these compounds reduce reactive oxygen species, stabilize mitochondrial membrane potential, enhance mitophagy, and activate NRF2 dependent transcription, which translates into attenuation of ASD like behaviors in VPA, propionic acid, maternal immune activation, and BTBR paradigms (De Mattos et al., 2020