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At mouse embryonic day (E) 8.0, a proportion of cells in ventral foregut proximal to mesodermal cells adopt a hepatoblast (HB) fate, being bipotent for hepatocytes and cholangiocytes (Lotto et al., 2023)

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The authors concluded that TB4 is a multifunctional regenerative peptide important in dermal repair, acting through promotion of cell migration, stem cell mobilisation and differentiation, and inhibition of inflammation and apoptosis