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those with diabetes or obesity but no medication (300,000 patients in the study) Those on GLP-1 meds were 66% more likely to have gastroparesis 0.53% of patients had paralysis that is the equivalent of 1 in every 200 people on semaglutide or tirzepatide They were more likely to have nausea, vomition, or reflux and be prescribed a proton pump inhibitor They were more likely to have drug-induced pancreatitis and need gallbladder removal

Gastrointestinal issues such as nausea, vomiting, diarrhoea, and constipation is common among users

Overeating During Weekends Undoes Weekday Gains Many people stick to healthy eating during the week but then lose control over the weekend

Plasma levels decline with age from about 200 ng/mL at age 20 to roughly 80 ng/mL by age 60