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In this article, we briefly review molecular aspects of each component (the antibody, payload, and linker) of ADCs, and then mainly discuss traditional and new technologies of the conjugation and linker chemistries for successful construction of clinically effective ADCs

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Viral infections activate endosomal NOX2 oxidase and restrict TLR7 signaling, and inhibition of endosomal NOX2 decreases viral pathogenicity 42

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