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Based on receptor-mediated targeting, BDPR NSs can effectively cross the BBB, target dopaminergic neurons, specifically clear ROS and reduce iron aggregation in PD lesions, and exhibit good neuroprotective effects in PD cell, nematode, and mouse models (226)
doi: 10.1111/dom.13361
Hanefeld M, Brunetti P, Schernthaner GH, Matthews DR, Charbonnel BH (2004) One-year glycemic control with a sulfonylurea plus pioglitazone versus a sulfonylurea plus metformin in patients with type 2 diabetes
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