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The study also revealed a statistically significant drop in IOP after starting GLP-1 receptor agonist treatment, especially in those with a history of glaucoma or pre-existing excessive IOP. The researchers also found that GLP-1 agonist use in the management of type 2 diabetes may have possible cardiovascular advantages

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Melanotan II activates melanocortin receptor signaling primarily through Gs-mediated cAMP pathways and also influences downstream neuroendocrine circuits involved in appetite control