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( Glutathione: a key player in autoimmunity, Carlo Perricone, Caterina De Carolis, Roberto Perricone, Autoimmunity Reviews, 2009, doi: 10.1016/j.autrev.2009.02.020., ( Effect of Glutathione Infusion on Leg Arterial Circulation, Cutaneous Microcirculation, and Pain-Free Walking Distance in Patients With Peripheral Obstructive Arterial Disease: A Randomized, Double-Blind, Placebo-Controlled Trial, Enrico Arosio, MD, Sergio De Marchi, MD Massimo Zannoni, MD, Manlio Prior, MD, Alessandro Lechi, MD, Mayo Clinic Proceedings, DOI: (

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Downregulation of the p53 signaling pathway promotes cellular proliferation and modulates inflammatory responses 71 , while HDAC7 depletion facilitates cell migration, angiogenesis, and extracellular matrix remodeling, collectively contributing to coordinated tissue repair 72