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The last step of GSH biosynthesis involve the addition of Gly by ATP and Mg2+ dependent glutathione synthase (GS)

We have also showed that other markers of DNA damage/cell cycle (p21, p53, p57 and phospho-p57, GADD45, 8-OHdG), apoptotic (BCL-2, CASP-2, CASP-9) and anti-oxidant pathways (GP-1, SOD-1, HO-1, p38 stress kinase), that are not specifically associated with hair follicle pigmentation, have distinct expression patterns and colocalise to parts of the hair follicle such as the IRS, ORS, DP and cortex

Medicaid coverage through Anthem varies by state