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(2019) UVA and UVB radiation induce the formation of neutrophil extracellular traps by human polymorphonuclear cells

On the other hand, human-derived models, such as primary human cells, human induced pluripotent stem cells (hiPSCs), and hiPSC-derived organoids offer distinct advantages

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The slightly greater HMOX1 induction by heme compared with heme-HPX is because the rate of heme diffusion into cells is significantly faster than the gradual, relatively slow and safe heme delivery via heme-HPX endocytosis (Smith and Morgan, 1981)