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Melanotan-1 is an MC1R agonist

New therapeutic approaches that use drugs to ameliorate the downstream sequelae of HbS polymerization have not proved to be as effective as hydroxyurea (HU) which has an anti-sickling effect via induction of fetal hemoglobin (HbF, 22) (Ware and Aygun, 2009)

Safety depends on which peptides are combined and whether the protocol is supervised by a licensed provider