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It means we have less definitive evidence for tirzepatide's cardiovascular benefits compared to semaglutide

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Lillys versions have recorded a more powerful weight loss effect, believed to be due to a dual-action on two hormones (GLP-1 and GIP)

[14] [13] These mechanisms contribute to improved glycaemic control and weight loss, but they can also lead to reduced caloric intake, changes in eating patterns, and occasionally low blood glucose levels (hypoglycaemia), all of which may contribute to feelings of tiredness