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This overlap suggests a complex interaction between oral and intestinal microecology, where oral bacteria can colonize the gut, significantly influencing various pathophysiological processes

Recently, a specific knockout of the tropomyosin-related kinase B (TrkB) receptor in hippocampal neural progenitor cells was performed by crossing mice harboring the TrkB flox alleles to transgenic mice expressing the Cre recombinase under the human glial fibrillary acidic protein promoter or the Synapsin 1 (Syn) promoter

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Quantitation was performed using a 10-point internal calibration standard (ranging from 0.05 to 450 ng/mL) based on the primary MRM ion abundance of BPA to that of the associated IS (215.5 m/z)