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Conversely, some patients report temporary digestive changes as their system readjusts to the absence of the medication

7 earnings call, Eli Lilly CEO David Ricks told investors that the company plans to submit the drug, orforglipron, to the FDA for approval by the end of the year

Most nausea is mild and eases as your body adjusts, though severe or persistent symptoms are worth a call to your clinician

Call a provider if: side effects are getting stronger instead of weaker you cannot eat or drink enough to stay hydrated you lose weight so fast that you feel weak and unwell you have ongoing pain that does not make sense Going to urgent or emergency care is important if you have: trouble breathing chest pain sudden, strong stomach pain signs of a severe allergic reaction Who Should Be More Careful with GLP-1 Medicines GLP-1 medicines are not the right fit for everyone