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The role of allergy in this skin disease has been controversial but it has been shown that in the majority of patients, allergic reactions -- preferentially by IgE-mediated sensitization -- seem to play a clinically relevant role in eliciting and maintaining eczematous skin lesions
An altered gut microbiota, referred to as dysbiosis, not only induces increased intestinal permeability locally, but also promotes systemic immune responses in the CNS
The discovery of GLP-1 receptors in the central nervous system has opened new avenues for understanding how these medications might influence brain health
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