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As a result, GLP-1 medications are FDA-approved specifically for chronic weight management, and are recommended by major medical organizations as part of a comprehensive weight loss program

A recent systematic review and meta-analysis demonstrated increased small intestinal and whole gut permeability in MAFLD patients, even if this was not confirmed in all individual studies (134, 140, 141)

The manufacturers supporting these programmes must allocate significant cleanroom space, automation infrastructure, engineering resources, quality oversight and supply chain bandwidth to them

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