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Nucleic Acids Research, 48 , 82258242

NAC has shown therapeutic promise when used alone or in combination with stem-cell based bone tissue engineering for alveolar bone defects caused by periodontitis

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While high doses administered over a short duration can induce symptoms such as lethargy, decreased food consumption, and weight loss in these animals, no significant mortality has been observed within specific dosage limits (Mihailovi et al., 2013)