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Furthermore, it has been demonstrated that p53 exerts a direct inhibitory effect on DPP4 in a transcription-independent fashion, thereby impeding the occurrence of ferroptosis (Xie et al., 2017
Montanya E, Rosenstock J, Canani LH, et al
The disconnect between this promising science and clinical application is stark: not a single human trial exists for mental health applications, leaving patients and clinicians with compelling mechanisms but zero human efficacy or safety data
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