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So people at greatest risk for deficiency include those with low stomach acid (e.g., older adults and people on proton pump inhibitors or antacids) or low IF production (known as pernicious anemia), people on medications that interfere with B12 absorption (such as metformin), people who have had gastric surgery, those with GI conditions that impair nutrient absorption (like celiac or Crohn's disease), and people on vegan and vegetarian diets

However, it is also a very important oxidation-regulating compound, thus melanin serves as a protective mechanism against UV exposure

As more research and controlled trials become available, we will better understand how to optimize GHK-Cu treatment identifying the best doses, patient types, and protocols

Individual responses to 5-Amino-1MQ vary significantly, and what works optimally for one person may require adjustment for another