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A documented taper plan if stopping is on the table, with weight, body composition, and cardiometabolic markers tracked through the taper and for at least 12 months after

To compare the predictions of our model to the patient records, we used their predictions of size and timing of dose for each of the 53 patients

The magnitude of improvement seen with retatrutide, driven by its greater weight loss, represents a potentially significant advantage for researchers dealing with obesity-related joint conditions

However, evidence in patients with prior pancreatitis is limited, which is why individualized medical judgment is essential