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It is thought to work by mimicking many of the biological effects of exercise

Key approaches include: Caloric awareness : Maintaining a modest caloric deficit (200300 kcal below maintenance) or at minimum, precise caloric balance Protein prioritization : Consuming 1.21.6 g/kg body weight daily to preserve lean mass and enhance satiety (with appropriate modifications for those with chronic kidney disease or other conditions requiring protein restriction) Volumetric eating : Emphasizing high-fiber, low-energy-density foods (vegetables, fruits, whole grains) that promote fullness Meal structure : Regular eating patterns with planned meals and snacks to prevent impulsive consumption Physical activity intensification becomes critical post-discontinuation

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Whilst the medication can be highly effective for glycaemic control and weight management, the resulting body composition changes may require practical adjustments