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doi: 10.3389/fphar.2025.1620870 Received 06 May 2025 Accepted 25 June 2025 Published 11 July 2025 Volume 16 - 2025 Edited by Kefang Sun, Rochester General Hospital, United States Reviewed by Irena Mladenova, Trakia University, Bulgaria Chengu Niu, Rochester Regional Health, United States Hsi-Chang Shih, Johns Hopkins University, United States Updates Copyright 2025 Yuan, Yang, Han, Yang and Tu