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Important Note on the Evidence Base Important note on the evidence base: The Dihexa research literature is entirely preclinical rodent behavioral models, in vitro hippocampal neuron culture, and mechanistic work characterizing HGF/c-Met-dependent signaling

J Neuroinflammation 15(1):337 Kim DS, Choi HI, Wang Y, Luo Y, Hoffer BJ, Greig NH (2017) A new treatment strategy for Parkinsons disease through the gutbrain axis: the glucagon-like peptide-1 receptor pathway

Oral versus injectable semaglutide Oral semaglutide (Rybelsus) has lower bioavailability than injectable forms, meaning more of the drug is lost to first-pass metabolism in the gut and liver

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