retatrutide approval status october 2025 Compounded Semaglutide vs Wegovy vs Ozempic Hims & Hers Offer Ozempic

In the diabetes TRIUMPH-2 trial, reported side effects included: Diarrhea (around 27 to 34 percent of participants, depending on the dose) Nausea (14 to 28 percent) Constipation (14 to 17 percent) Decreased appetite (6 to 17 percent) Vomiting (6 to 16 percent) In the TRIUMPH-3 trial for adults with severe obesity and heart disease, participants reported: Diarrhea (around 24 to 30 percent of participants, depending on the dose) Nausea (22 percent) Constipation (16 to 18 percent) Decreased appetite (14 to 15 percent) Hyperglycemia, or high blood sugar (3 to 4 percent) The high rates of diarrhea surprised Ali

How to Manage and Minimize Retatrutide Side Effects Mild gastrointestinal symptoms may occur during treatment with incretin-based therapies, particularly during dose escalation

Kunyahamu MS, Daud A, Jusoh N

& Mathieu, C