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Common Side Effects and Safety Considerations Gastrointestinal side effects are the most frequently reported adverse reactions with GLP-1 receptor agonists, affecting a substantial proportion of patients, particularly during treatment initiation

There is a theoretical concern that aggressive senolytic clearance could remove this anti-tumor senescence signal, potentially accelerating tumor growth in individuals with pre-malignant cells

[16] [35] [36] Stephen Chiodo was to direct the movie, and his brother Charles would be a production designer