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As shown in the inset, NAC (40 mm) significantly attenuated the mucosal injury by 5060% with respect to TNBS+ethanol-treated rats in the absence of NAC

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A meta-analysis published in The Lancet Diabetes & Endocrinology (N=17 prospective studies) found that individuals in the highest quintile of circulating IGF-1 had a 25% increased relative risk of colorectal cancer compared to the lowest quintile [12]

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