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The selectivity profile of 5-amino-1MQ is particularly noteworthy for research applications, as comprehensive enzyme panel screening reveals no inhibition of related SAM-dependent methyltransferases or enzymes in the NAD+ salvage pathway at concentrations up to 10 M

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Although all RCTs were carried out in one single center, in Italy, we have ensured that the 7 RCTs had high-quality Jadad scores and no significant publication bias showed through statistical tests