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[6] [7] If sleep problems persist beyond the initial adjustment period (typically 36 months), your clinician may recommend: Comprehensive sleep assessment Review of concomitant medications that might affect sleep Evaluation for mood disorders, which can both cause and result from poor sleep Consideration of whether treatment benefits outweigh persistent side effects Maintaining realistic expectations about the treatment journey, including the possibility of temporary side effects, helps patients persist with therapy long enough to achieve meaningful health benefits

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