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I didnt believe it in the beginning, but I do now. Reporting for this article was supported by a grant from The Water Desk, an initiative based at the University of Colorado Boulders Center for Environmental Journalism.

The clinical titration starts at 0.25 mg weekly and increases every four weeks up to a maintenance dose of 2.4 mg weekly, though some research protocols extend up to 4.5 mg

doi: 10.1111/j.1526-4637.2009.00613.x PMCID: PMC2891387 NIHMSID: NIHMS209741 Fibromyalgia Symptoms Are Reduced by Low-Dose Naltrexone: A Pilot Study Jarred Younger, PhD and Sean Mackey, MD, PhD Clin Rheumatol

Choose the right form Look for methylcobalamin, the active, bioavailable form of B12