Serious reactions are exceptionally uncommon but can include allergic responses in sensitive individuals
Dosage table: Horse, Large cattle 1 2 ml per animal Calf, heifer, foal 1 2 ml per animal Sheep, goat 1 2 ml per animal Lamb 0.25 0.5 ml per animal Dog 0.25 0.5 ml per animal Cat 0.25 0.5 ml per animal Or calculate the dose for dogs 50 200 mcg per Kg and cats 50 100 mcg per Kg live weight and re-administer every 1 2 weeks if needed
TLR4 can enhance the production of pro-inflammatory cytokines and chemokines, such as IL-6 and IL-17, by binding with exogenous ligands, like peptidoglycan, in FLS and peripheral blood mononuclear (PBMC) from RA patients, and trigger cartilage inflammation and degeneration (135)
Treated wounds also show increased collagen deposition and enhanced angiogenesis, with new blood vessel formation supporting healing tissue with improved nutrient delivery