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Studies report that curcumin increases glutathione S-transferase (GST) activity in the liver

[11] While the landmark study was conducted on older adults, its findings suggest potentially broader implications

Localized application focuses on injured areas (tendon strain, muscle tear), while systemic use supports overall recovery balance

Specifically, research shows that Bifidobacterium adolescentis is a high GABA producer.[ref] Lactobacillus brevis DPC6108 and Lactobacillus rhamnosus are also probiotic strains that produce GABA.[ref][ref] A 2024 double blind placebo controlled trial found that a probiotic formulation of Lactobacillus brevis and Lactiplantibacillus plantarum reduced symptoms of depression and improved mood, but did not affect stress levels