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If you live in a city with high pollution, travel frequently, or have a high-stress job, your body is likely using its glutathione stores faster than someone in a more relaxed environment

Oxidative stress is essentially biological rusting

From the cardiovascular system: tachycardia, arrhythmia, bradycardia, transverse heart block, cardiac arrest, peripheral vasodilation, collapse, pain in the heart, increased or decreased blood pressure, slowed heart conduction

The free apo-peptide binds copper(II) with high affinity through its N-terminal amine, the histidine imidazole nitrogen, and the deprotonated amide nitrogen, forming the GHK-Cu species that figures in much of the published literature