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In recent years, involvement of GSTs in different processes such as modulation of cell signaling kinases, formation and modulation of ion channels, oxidation-reduction reactions, and the post-translational glutathionylation of proteins have been outlined ( Different Classes and Catalytic Mechanism of GSTs Though the classification and nomenclature of GSTs in plants and animals are conundrum, however, they have been distinctly categorized into three families

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however, its blood pressure-lowering effect appears less than those of spironolactone and eplerenone (both steroidal mineralocorticoid receptor antagonists)