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Statements Data availability statement The original contributions presented in the study are included in the article, further inquiries can be directed to the corresponding author

Among patients who persisted with their medication one year after their initial prescriptions, the proportion who achieved 10% or more weight reduction was 61% with semaglutide for obesity, 23.1% with semaglutide for type 2 diabetes, 28.6% with liraglutide for obesity, and 12.3% with liraglutide for type 2 diabetes

As circadian rhythms are prevalent within physiological processes within the gut [8], there is the potential for some time-of-day variability in the absorption of orally administered drugs and in the speed of gastric emptying following a meal [8, 9]

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