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As mentioned earlier, the increased intake of proteins (processed, red meats), sugars, salt, saturated and trans fat, and refined carbohydrates, which are characteristic of the Western-style diet, leads to the development of many diseases, which have their basis in the occurrence of OxS (135)
Indeed, B cells were proposed to promote fibrosis primarily through their ability to amplify hepatic inflammation, with MyD88 signaling required for fibrosis progression
Therefore, the release of DNAzymes from the formulation was found to follow Korsmeyer-Peppas kinetics, suggesting an anomalous (non-Fickian) diffusion release mechanism